Replery drugs: which one is right for you

In this article we will look at the Repleri line of fillers. What they contain, how effective they are and for what areas, how injections are made and what complications there may be. In addition, we will get acquainted with the opinions of cosmetologists and patient reviews, prices in Moscow clinics, photographs of patients before and after the procedure.


Repleri fillers

How do Repleri drugs work?

Hyaluronic acid is an important component in the human body. It is entrusted with the functions of regulating water balance and participating in the formation of elastin and collagen. In youth there are no problems with its synthesis, so the skin is elastic and smooth. With age, synthesis decreases, the first wrinkles appear, and the skin becomes dry.

Therefore, hyaluronic acid is introduced from the outside, this allows it to act directly on the required area.


How hyaluronic filler works

During the injection, Repleri gel fills the subcutaneous voids, thus smoothing out wrinkles and creating ideal contours. And due to the presence of hyaluronic acid in the composition, its deficiency is compensated. The result is hydrated, smooth skin, without sagging or wrinkles.

Advantages over other manufacturers

The manufacturer cites several main advantages over other fillers:

  • Density. Repleri is a biphasic filler with particles of different sizes. This increases the density of the gel, so after injection it lasts up to a year and does not dissolve.
  • When administered, no collagen is formed. This ensures that the client is not at risk of fibrosis after the procedure.
  • Safety. The drugs are the most studied fillers among others on the Russian market. The studies were conducted both in an artificial environment and on patients. According to experts, injections are safe and create a long-lasting aesthetic effect.
  • Wide range of applications. Repler 1 is used to work in the areas around the lips and eyes. Replery 2 - for getting rid of small wrinkles, lip correction, for non-surgical rhinoplasty. Repler 3 eliminates deep wrinkles, enlarges lips and adds volume to cheekbones. In addition, it is used in intimate contouring. Repleri 4 is used to correct cheekbones and the shape of the chin. The 5th is used in the same areas as the 4th, but it can be used for contouring of the nose. The Lip series is designed to correct the volume and contour of the lips.

Replery series of drugs

The series includes six intradermal fillers, which differ from each other in gel density and particle size. The filler for lip contouring Repleri Lip is presented separately.

Repleri 1

Replery 1 – has the smallest size of hyaluronic acid molecules. Injected mainly into the upper layers of the epidermis. The drug is used for mesotherapy and biorevitalization to eliminate facial wrinkles, correct lip contour, prevent aging and deeply moisturize the skin.

Repleri 2

Replery 2 – the gel contains medium-sized molecules of the active substance. Injected into the papillary dermis. Used to correct wrinkles in the forehead and nasolabial triangle, sculpt the chin, correct cheekbones, moisturize and improve lip contour.

Repleri 3

Replery 3 is the optimal preparation for filling deep nasolabial folds, smoothing wrinkles and restoring the volume of soft tissues of the face (filling voids on the back and near the wings of the nose). Used for non-surgical plastic surgery of the nose and cheekbones.

Repleri 4

Replery 4 - a gel consisting of large molecules of hyaluronic acid, injected into the hypodermis or periosteum (the surface layer of the facial bone). Used for contouring in the area of ​​the cheekbones, temples and chin.

Replery 5

Repleri 5 is an intradermal filler with a large particle size of the active substance, which is injected into the periosteum area. Used for non-surgical skin tightening, restoration of volume of cheekbones, cheeks and chin.

Repleri Lip

Repleri Lip is a hyaluronic filler for contouring in the lower third of the face. Used to correct the shape and increase the volume of the lips, as well as smooth out wrinkles in the perioral area. Injected into the depth of the papillary dermis.

How is the procedure done?

The procedure, together with local anesthesia, takes no more than 45 minutes. Sometimes several drugs are administered at once, depending on what purpose is being pursued.

Preparing for injections

Basic recommendations for preparing for contouring:

  • refusal of drugs that reduce blood clotting 2 days before and after the procedure;
  • abstaining from alcoholic beverages, visiting a sauna or solarium, 5 days before the injection. You cannot visit the solarium for a month after the procedure;
  • taking homeopathic remedies based on arnica 5-7 days before the procedure and 2-3 days after. This will prevent bruising.

Administration techniques

The method of administration of Replery depends on which area is planned to be corrected and with what drug. There are four main techniques:

  • Linear. Used when introducing a gel of medium density molecules into the upper layers of the skin. A thin needle is inserted to its full length at an angle of 30 to 40 degrees.
  • Fan. Injections are carried out according to the principle of linear technology. The main difference is that the needle is not removed after injection, but is turned under the skin in the opposite direction. Next, the introduction of the gel continues.
  • Mesh. The technique is used when working in the temporal part of the face, with cheekbones and cheeks. The gel is injected parallel and perpendicular, thus obtaining a soft filling effect.
  • “Sandwich.” Used when working with deep changes on the facial skin. The gel is introduced in two stages onto different layers of the dermis. The needle enters the deep layers at an angle of 30 degrees, and into the upper layers - 15 degrees.

Procedure step by step

Let's look at the step-by-step procedure using the example of cheekbone and lip augmentation with Repleri filler:

  1. Cosmetics are removed from the skin, and the area where the gel is introduced is disinfected.

  2. The drug administration is marked.

  3. An anesthetic cream is applied.
  4. The packaging with the drug is opened and the expiration dates are checked. Everything happens in the presence of the client.
  5. Administration of the drug.

  6. Repeated skin disinfection.
  7. Light massage, application of an anti-inflammatory agent.

Areas of use


Contour plastic

Replery filler was developed primarily for contouring. With its help, you can adjust the shape and volume of the lips (in particular the borders), change the shape of the bridge of the nose, earlobe, chin and cheekbones, and get rid of jowls. The intradermal filler smooths out fine and deep forehead wrinkles, provides non-surgical lifting of the eyebrows and temporal zone, eliminates nasal and marionette folds, and eliminates perioral folds.

Repleri Security

Replery is the most studied drug in Russia in comparison with other fillers. Every year since 2008, it undergoes clinical trials.

Since 2021, additional analysis has been carried out in China according to international standards. Each new batch is tested on 100 volunteers. Half are doing the correction for the first time, the other half are doing it again. The filler is injected into the chin, lips, nasolabial folds, nose, cheekbones, and periorbital area. Company experts monitor patients for six months. Communication with patients occurs through a special application. After ensuring quality and safety, Repleri is sent to Moscow.


Repler is one of the most studied fillers in Russia

In addition, the company offers training for cosmetologists and the use of the PatientStory application to quickly respond to all requests and the patient’s condition. The main values ​​of the company: positive customer history and repeat business.

The use of non-animal hyaluronic acid in Repleri fillers makes them completely safe. Allergic manifestations are excluded. Injections, unlike synthetic implants, do not cause negative consequences.

And if you don’t like the result, everything will return to its original state within a year. This is possible due to the fact that hyaluronic acid completely disintegrates.

To achieve an ideal result, you need to choose the right Repler number. Adhere to the technique of inserting and deepening the needle. Failure to comply with these two factors can lead to poor filling of wrinkles and incomplete aesthetic effect.

Video: How Repleri is made

Possible complications and side effects

No specific complications were identified with the use of Repleri drugs. Side effects include:

  • swelling, which could be caused by the wrong choice of the drug series;
  • the appearance of seals or balls occurs more often with lip augmentation. The reason is a violation of the introduction technology;
  • inflammation is possible if the rules of asepsis are not followed or if the process of inflammation began even before the procedure. Hyaluronic acid itself is not capable of causing suppuration, but can become an activator of the process.

Injections using Repleri intradermal gels can only be performed by qualified specialists: cosmetologists, dermatologists and maxillofacial surgeons. A reliable doctor is the key to a healthy and safe procedure.

Compatibility with other fillers

Sometimes the question arises with what other fillers can Repleri be safely combined so that it is safe but effective. The answer is simple, any two-phase preparations with the main active ingredient in the form of hyaluronic acid.

Here is a list of some of them:

  • Restylane - eliminates the absence of soft tissues, used in the correction of wrinkles;
  • Perlane contains stabilized particles of sodium hyaluronate. The gel is used to correct the shape of the face and fill deep folds;
  • Perfecta is an implant of biotechnological origin. It is used for modeling lips, facial contours and skin plastic surgery.

Understanding the markings

This drug for each age category is distinguished by its marking and its characteristic needle and syringe sizes, accordingly with which it will be injected under the skin. The filler is packaged in a special syringe, which is opened immediately before the procedure and in the presence of the client.

1st Repleri is recommended to be used from the age of 25 to correct minor imperfections in the main problem areas: apply to the eyelids, lip areas, their contour and the bridge of the nose. This filler injects shallowly, has very small particles and is mainly used to prevent aging.

The 2nd Repler is intended for deeper skin layers and correction of more serious imperfections. It is injected into clients over 35 years of age in order to eliminate some wrinkles, get rid of wrinkles on the forehead and bridge of the nose, and correct the outer edges of the eyebrows in order to make the look more open.

The 3rd Repler is also intended for people over 35 years of age, but the results here will be more stable and long-lasting. With the help of filler, deeper wrinkles are eliminated and the entire facial contour is generally smoothed out. With its help you can emphasize your cheekbones and make your cheeks plump. The particles here are slightly larger than average.

The 4th Repler contains the largest molecular particles, and their density is not as high as in previous versions. The filler is injected into the areas above the bones and into the deeper layers of the skin to correct the oval of the face and lipid tissues. Targeted at ages 45 and up.

5th Replery is the most large molecular filler with hyaluronic acid for clients over 50 years old. Here it is already completely introduced into the areas above the bones, because at this age it already forms lumps in the skin itself. It is aimed at getting rid of deep wrinkles near the mouth, shaping cheekbones and facial contours and correcting nasolabial folds.

The filler number three is the most popular, since this is a kind of middle ground and is most often asked for in beauty salons due to the fact that few people use such drugs before the age of 35, and after reaching that age more careful care will be required.

For the most part, the success of the entire procedure depends on the professionalism of the specialist who will carry it out. The most experienced dermatologist will know for sure which medications can be mixed and combined, and will also be able to give quality advice on proper skin care and further treatment.

Cost of injections in Moscow clinics

Clinic nameA drugprice, rub.
CLINICA IDEALRepleri No. 4 – 1.5 ml14 000
Repleri No. 5 – 2.0 ml15 000
MedCenterServiceRepleri №2 – 1ml10 350
Repleri №3 – 1ml11 000
Medical cosmetology clinic "Aida"Repleri Lip – 1ml16 000
Repleri №1 – 1ml15500
Repleri №2 – 1ml15500
Repleri №3 – 1ml15500
Repleri №4 – 1.5ml17500
Repleri №5 – 2ml23000
Medical-surgicalRepleri №3 – 1ml11500
Repleri №4 – 1ml13500
Repleri №5 – 2 ml17000
Arbat Esthetician, expert cosmetology clinicRepleri №1 – 1ml11600
Repleri №2 – 1ml11600
Repleri №3 – 1ml11600

The price of the drug depends on its density; in comparison with other brands, Ripplery is a little cheaper.

Only a cosmetologist determines how much and what kind of drug is needed for correction. It is possible that several fillers will be used at once.

Cost of Repler fillers

The price for 1 ml of the drug does not change, but the cost of the drug will vary depending on the labeling. Filler of each marking is produced by the manufacturer in different volumes. There is no need to calculate the cost of the procedure by multiplying the cost of a milliliter by the required quantity, since the optimal amount of the drug is established by the manufacturer. But the doctor may additionally prescribe a filler of a different label.

In general, this is 7,000 rubles. for 1 ml. The first three types of filler are sold in quantities of 1 ml in a syringe, No. 4 - 1.5 ml, No. 5 - 2.5 ml. In addition, you need to take into account that the correction will be symmetrical, and the beauty injection must be done on both the right and left. You will need two syringes, or more, depending on the instructions of the cosmetologist.

The approximate price of 1 ml of the drug is 7,000 rubles

Photos before and after


Photos before and after lip augmentation Repleri No. 1


Photos before and after correction of lower corners with Repleri filler


Photos before and after Repleri reconstructive contouring (cheekbones and chin)


Photos before and after complex contour plastic surgery Repleri (cheekbones, temples, chin, eyebrow lifting, forehead lifting, non-surgical rhinoplasty)


Photos before and after chin augmentation Repleri No. 5


Photos before and after lip correction – 1 ml Repleri No. 3

Main stages of the procedure

Before the procedure, the injection sites are lubricated with anesthetic. If the patient is already familiar with the procedure or has reduced sensitivity, then an anesthetic can be dispensed with. Creams or injections may be used to relieve pain.

Injection-type painkillers act very quickly and relieve the patient of any pain. Antiseptic creams take effect within thirty minutes and do not provide complete pain relief.

After anesthesia, the skin is treated with an antiseptic to prevent infection. The time of one session depends on the tasks facing the cosmetologist. On average, the procedure lasts from fifteen minutes to an hour.

NovoNexus - contour plastic surgery Repleri.mp4

Cosmetologists' opinions

Basically, cosmetologists speak positively about Replery gels. Specialists are attracted by the price-quality ratio. But there are those who do not trust, citing the production of the gel in China.

For example, a cosmetologist is completely satisfied with the line and actively uses it in practice.

And this cosmetologist uses Repler 4 and 5 in his work, but emphasizes that the effect of fillers is less compared to others.

Another cosmetologist compares Replery with other fillers and recommends choosing a good doctor, not a clinic.

Contraindications to procedures, side effects

The injection of repler filler is prohibited:

  • in case of individual intolerance to certain elements of the drug;
  • during the period of bearing a child and breastfeeding;
  • for autoimmune diseases and pathologies associated with blood clotting.

Possible side effects caused by the introduction of repler fillers appear immediately after the end of the procedure and disappear in the shortest possible time (2-3 days).

Side effects appear as:

  • small bruises and bruises at the injection sites of the filler;
  • redness and swelling of the treated area.

There are also risks of developing specific adverse reactions of the body to the administered drug:

  • the formation of persistent edema is associated with incorrect selection of the drug (replery filler 4 and 5 cannot be used for lip correction);
  • the appearance of small compactions is caused by violations of the drug administration technique;
  • acute inflammatory processes in the treated areas - the cause of a side effect may be insufficient antiseptic treatment of the skin and filler injection instruments.

Patient reviews

Among the patients there are those who are not the first to enlarge their lips and were in search of their own remedy. But it is Replery that becomes a permanent drug.

For a quick result and long-lasting effect for lip correction, the patient, on recommendation, chose Replery and was satisfied.

Another patient had her nasolabial lips corrected; she is familiar with the entire line of fillers and knows the manufacturer. I'm happy with the result.

Here the woman also had her nasolabial folds corrected. In the review she writes that she is satisfied with the result and believes that this is a good drug. It also notes a lasting effect.

Popular questions

Are injections a painful procedure?

Yes, the procedure is painful, so it is performed with anesthesia.

Are the injection sites visible?

Redness at the injection site, slight itching, and tension may appear. The injection mark and swelling disappear after a few days.

What does your face look like after Repleri cheekbone correction?

The effect is visible immediately after administration of the drug, but you can evaluate the final result after 14 days. During this period, the swelling will subside, and it will be clear which areas require additional correction.

How to get rid of swelling faster?

Immediately after the injections, apply ice and use medications prescribed by your doctor. In the case of lip correction, you need to smile less and avoid the sun.

How does skin sensitivity change?

Sensitivity does not decrease; there may be a slight decrease only immediately after the injection.

Does facial expression change after injection?

If the injection technique is followed, the facial expression will remain the same.

How long does the effect of the procedures last?

The drug is absorbed gradually. The effect disappears after 5-12 months, depending on the filler and injection site.

Side effects

  • bruises from injections;
  • itching;
  • allergy to anesthetic, antiseptic or filler;
  • tissue necrosis at injection sites;
  • fibrosis (the appearance of nodules that should resolve in a couple of weeks);
  • flow of filler from one area to another.


The effectiveness of Replery gel is noticeable to the naked eye!

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