Contour plastic surgery with fillers based on calcium hydroxyapatite of the cheekbones, temporal areas, chin

PinterestThe use of any off-label drug, that is, not according to indications, is an undertaking at your own peril and risk. We will tell you in which areas of medicine, besides aesthetics, Botox is used, and whether it is always safe.
Botulinum toxin is a neurotoxin produced by the bacteria Clostridium botulinum, which in turn causes botulism. This disease causes life-threatening nerve palsy. There are seven types of toxin, but only three of them primarily cause human botulism - A, B, and E.

In 1989, the Food and Drug Administration (FDA) approved the use of botulinum toxin to treat strabismus and blepharospasm (spasm of the eyelids). In 2002, the FDA approved its use in the field of dermatology and cosmetology for the treatment of moderate to severe glabellar lines (glabellar lines). Two years later, the indications for botulinum therapy expanded, and it began to be actively used for axillary hyperhidrosis (excessive sweating).

Today, six botulinum toxin preparations are registered in Russia. It is also included mandatory in the standard of treatment for cerebral palsy. The final effect of the toxin is to reduce sweating, reduce pain at the injection site, and temporarily paralyze the target skeletal muscles.

Off label injections - how it is

Off label
means the procedure is not carried out for its intended purpose. In other words, the doctor takes responsibility and selects doses based only on literature data, as well as his own experience and the experience of colleagues. It must be noted that the FDA recognizes the possibility of a physician using any approved product with deviations from the existing instructions. Thus, a specialist can decide to carry out botulinum therapy, and this will not become a crime. At the same time, you can resort to off-label treatment only if there are compelling reasons. We must not forget that the main goal is the effectiveness and safety of injections.

Indications for botulinum therapy

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This treatment method is widely used in dermatology, ophthalmology, neurology, urology and gynecology, as well as gastroenterology.
As mentioned earlier, blepharospasm, increased sweating, and wrinkles are corrected with botulinum toxin. But what other problems can be solved? Here is a list of diseases for which treatment with botulinum toxin is indicated:

Strabismus
Migraine
Cervical dystonia (acute neck spasms)
Spasticity of the upper/lower extremities (increased muscle tone)
Overactive bladder (sharp, difficult urge to urinate)

Diseases for which botulinum therapy is performed in off-label mode:

Jaw trismus (spasm or involuntary movements of the chewing muscles)
Lower back pain
Depression
Premature ejaculation
Symptoms of Parkinson's disease
Anal fissures
Hypersalivation (salivation)
Bruxism (night/daytime) teeth grinding
Cleft lip (cleft palate)
Congenital nystagmus (congenital disorder of eye movement)
Tear hypersecretion (excessive production of tear fluid)
Angle-closure glaucoma - as pain relief
Facial asymmetry
Pain during intercourse
Painful bladder syndrome, urinary retention
Biliary dyskinesia (impaired flow of bile)
Postherpetic neuralgia
Raynaud's syndrome (vasospasm of the hands)
Vulvodynia (chronic pain in the vulva)
Psoriasis of flexor surfaces, etc.

Scope of application of calcium hydroxyapatite

Hydroxyapatite (hydroxylapatite) calcium or Hydroxylapatite is an inorganic substance that is an integral part of bones, enamel, and cells in the human body. It is present in tooth enamel and cellular structure. This is a synthetic substance that is obtained from marine corals.

The synthetic substance Hydroxylapatite belongs to the components that regulate calcium-phosphorus metabolism. It does not pose a danger to human life and health, and also does not have an active effect on human tissue. Therefore, it is actively used in various fields of medicine: dental, orthopedic, plastic surgery to restore the nose, jaw, and recently in the cosmetology field.

In tissues it is organized into crystalline structures, so it is used in the form of small microspheres.

In the field of cosmetology, preparations based on calcium hydroxyapatite are used as fillers to restore lost volumes. The fact is that the main sign of aging is not the appearance of wrinkles, but the sliding of the skin downwards, that is, a change in the “beauty triangle”.

A young face has the shape of an English letter V, which becomes “inverted” over time. This change is called deformational ptosis. The main volume is concentrated on the cheekbones, and the jawline is smooth.

It is important to note that its popularity in cosmetology is also increasing due to the virtual absence of complications.

We recommend reading about what vector lifting is. From the article you will learn about the differences between bioreinforcement and biorevitalization and contour plastic surgery, drugs and fillers for the procedure, and technique. And here is more information about DMAE mesotherapy.

Criterias of choice

Can't decide which drug to choose for facial rejuvenation using biorevitalization? A few useful tips will come in handy in this case.

Age

Keep in mind that some products are designed for light skin lifting at 35 years old, while others are designed for a large-scale tightening at 55. So be sure to ask at what age certain injections of beauty and youth are recommended. For example, we can note the following best drugs for biorevitalization after 50 years: Gialripayer 02 bioreparant and Meso-Wharton P199.

They do an excellent job with deep wrinkles, pigmentation, senile sagging and dry skin. If you are just beginning to experience age-related changes, you will be recommended other best drugs for biorevitalization after 40 years: Jalucomplex, CRM soft, Restylane vital.

Manufacturer country

In some countries, aesthetic medicine and cosmetology are very well developed. There are laboratory sites for research there. Their goal is to create the best drug for biorevitalization so that it has no analogues in this market. This affects the high quality of their products. But its price will be appropriate. If, for example, French brands are beyond any competition, then not all reviews of Korean hyaluronates are equally positive.

Quality

Often, clinic patients who undergo biorevitalization become hostages of their own inattention or even shyness. Only a few women ask the doctor for a certificate for the injection they will be given. But it is he who guarantees the safety and effectiveness of the drug. And don’t forget to inquire about the expiration date of hyaluronic acid, which should become your donor of beauty and eternal youth.

Be sure to ask your doctor what complications may arise after the administration of a particular drug. The smaller the list, the better the product.

Readiness

It is better to choose drugs that are already dosed in the package, in syringes. That is, the laboratory that produced them eliminates mistakes on the part of doctors, who themselves may introduce either too little (there will be no rejuvenation effect) or too much (consequences - multiple complications) of the product.

If you comply with all these criteria, choosing a drug for biorevitalization will not be at all difficult. If the clinic is good and the doctor is a true professional, he will definitely advise the client on this issue and give his recommendations. But still, a woman should already be familiar with the names of the products used. They offered something new that you had never heard of, claiming that it was the latest development? Don’t take your word for it: study the information and only then draw conclusions.

Properties used in cosmetology

As mentioned above, a sign of age-related changes is a decrease in skin density and elasticity, as well as a shift in volume from the upper part of the face to the chin. Several factors contribute to this process:

the effect of gravity;
decreased synthesis of collagen and elastin in tissues;
insufficient formation of hyaluronic acid in cells;
reduction in the number of fibroblasts in connective tissues.

As a result, turgor and elasticity decrease, the face becomes flabby, swollen, and “swollen.” The oval loses its clarity. The face takes on a sad, tired, mournful appearance. So getting rid of wrinkles is not enough. A young face is distinguished by elasticity and correct arrangement of volumes.

Due to its properties, calcium hydroxyapatite helps fill in lost forms. It fills wrinkles, returns clear lines and turgor to the skin.

Hydroxylapatite Hydroxylapatite in soft tissues provokes the production of natural collagen fibers in cells. It is introduced together with a conductor gel. After entering the tissue, the substance smoothes out wrinkles. It kind of pushes out the fold of skin and fills the space underneath it.

While macrophages, cells absorbing bacteria and toxins, eliminate the conductor gel, after which only Hydroxylapatite microspheres remain. They stimulate the production of natural collagen. The dermis becomes firm and elastic. Thus, a new tissue frame is formed by collagen fibers together with microspheres. The results from using the filler last for almost two years.

Expert opinion

Tatyana Somoilova

Cosmetology expert

But it is important to note that calcium hydroxyapatite does not moisturize, does not revitalize the epidermis, and does not transport beneficial substances into the deeper layers. Therefore, it is often combined with other procedures to improve skin condition.

When are fillers used?

Unfortunately, all people are subject to the natural aging process of the skin. With age, the production of collagen and elastin decreases, the skin and fat layer become thinner. As a result, free space appears and wrinkles form.

Special fillers are used to fill empty areas. Their task is not to dissolve, but to create additional volume. This ensures an excellent effect of the procedure.

Fighting wrinkles

The most common cosmetic defect is wrinkles on the forehead, around the mouth and eyes. When they appear, women panic and begin to spend unimaginable amounts on care products. Although the problem can be solved with just a few visits to a cosmetologist.

Today, to combat wrinkles, experts recommend fillers - dermal fillers that are injected and fill the free space. Due to this, tissue volume is restored.

There are several types of such drugs. They are created based on:

hyaluronic acid;
collagen;
poly-L-lactic acid;
calcium hydroxyapatite.

Active substances necessary for hydration, nutrition and restoration are added to the fillers as enhancers. Thus, the manufacturer provides a comprehensive solution to the aesthetic problems of facial skin.

Course duration

One of the features of using fillers is the cumulative effect. The result does not appear immediately, but lasts up to 1 year. Typically, 7-10 sessions are required to achieve the goal, with a break of several days.

The structure and condition of the skin gradually changes during this period. Pigment spots disappear, wrinkles are smoothed out, eyelids are lifted and jowls are eliminated.

Result

The use of fillers to combat age-related changes has been practiced for many years. Dermal fillers can help address common aesthetic concerns such as:

hyperpigmentation;
pimples and blackheads;
rosacea;
pale skin;
scars, scars;
"double chin;
dark circles, swelling under the eyes;
jowls and nasolabial folds;
facial wrinkles.

The introduction of fillers has an overall rejuvenating effect. Such drugs stimulate metabolic processes, saturate tissues with nutrients, vitamins and minerals.

Advantages of use in biorevitalization

Fillers have a number of advantages compared to other types. Calcium hydroxyapatite in cosmetology is becoming more and more popular among clients. All this thanks to:

The drug is biodergradable, that is, it is completely eliminated from the body after a certain time. However, it does not cause any harm.
This substance is related to the human body. It is not foreign, causing rejection and allergies. Therefore, the risk of complications is extremely low due to biocompatibility with human tissue.
Launching the production of endogenous collagen, that is, by the body itself.
The effect of calcium hydroxyapatite injections lasts much longer than other fillers. For example, it is twice as effective as hyaluronic acid.
The drug is independently placed in the tissues in an even layer. The result of biorevitalization with calcium hydroxyapatite becomes noticeable in less than a month.
It restores facial contours, not only moisturizes the skin and eliminates wrinkles.

Preparations with calcium hydroxyapatite

What is hydroxyapatite

Hydroxyapatite is a substance present in the organic matrix of bone tissue. Includes:

phosphorus;
calcium.

Contains macroelements magnesium, iron, zinc and boron. Its formula is similar to the structure of human bone tissue. Thanks to this property, it is positively absorbed by the body. Hydroxyapatite is often present in cosmetics in the form of nanoparticles. Found in nature in microcrystalline form. To obtain the drug, the substance is crushed to a white powder and mixed with purified water.

What can filler injections fix?

The use of this substance in cosmetology is quite extensive. Calcium hydroxyapatite filler is used to solve the following problems:

to fill missing volume in the cheeks, cheekbones and lower face;
for smoothing nasolabial folds;
elimination of “sorrowful” wrinkles in the corners of the mouth;
for a clearer oval;
smoothing the dermis on the hands, its rejuvenation;
to improve the tip of the nose;
against trophic scars and scars.

Indications and contraindications

The composition can be used in the following cases:

face shape correction;
filling of the nasolabial area;
elimination of wrinkles;
elimination of scars;
correction of cheeks, chin, cheekbones, ears, temples, nose, hands.

Using calcium hydroxyapatite, you can correct problem areas with a long-lasting effect.

The use of the drug may be harmful to health if the following deviations occur:

infectious diseases;
skin diseases;
oncology;
diabetes;
autoimmune diseases;
poor blood clotting;
pregnancy;
lactation;
menstruation.

When visiting your doctor, you must inform about the possibility of allergies and the medications you are taking.

Possible side effects and complications from use

Despite the fact that fillers with this drug are safe, there are some contraindications. You should not use the substance if you are hypersensitive or prone to allergies.

The procedure must be performed by a certified specialist who has been trained to work with calcium hydroxyapatite preparations. Traditional side effects are:

edematous phenomena;
small hematomas and bruises at the injection sites.

Tyndall effect
They go away on their own after a couple of days. If the specialist made a mistake and carried out the procedure with violations, the following complications may arise:

Due to insufficiently deep injection of filler, white streaks may form on the face.
if the drug fills unintended areas, such as the area around the eyes, lips, then lumps, asymmetry, and unevenness appear on the surface.
When the filler is injected shallowly, the substance may bleed through the skin. This is called the Tyndall effect.
If sanitary measures are violated, infection and suppuration may begin.
form clots and granulomas if the area has not been prepared for fillers.

Therefore, you need to contact only a highly qualified specialist. Otherwise, the consequences of violating the procedure protocol technique will take quite a long time to resolve.

Watch this video about the advantages and disadvantages of using calcium hydroxyapatite in fillers:

How do the procedures differ and what is better to choose?

Fillers and biorevitalization are considered cosmetic measures, and they are based on the targeted injection under the skin of drugs based on hyaluronic acid (you can find out more about fillers for contouring based on hyaluronic acid here).
However, these procedures differ in the nature of the manipulations and various indications for their implementation. Biorevitalization is recommended to eliminate imperfections in the dermis, and fillers are recommended to correct it and eliminate deep wrinkles and restore volume in the cheekbone area. Fillers are injected deep into the dermis, creating a framework that prevents skin sagging. Recommended for “slipping” of the face downwards.

The choice of one procedure or another depends on the patient’s skin condition, his preferences and the expected result. The cosmetologist decides what is more suitable for the patient – biorevitalization or fillers.

The following indicators are considered priority for both procedures:

lack of elasticity and firmness of the skin;
deterioration of metabolic processes in the skin;
unhealthy, dull complexion;
age-related disorders of facial contours.

Filler injections are performed with microneedles. A viscous substance based on hyaluronic acid with a dense consistency smooths out wrinkles, filling the voids under the skin. The effect after this procedure lasts from six months to a year, during which the drug is gradually removed from the tissues.

It is important that to maintain the effect, the procedure must be repeated periodically.

The duration of the effect depends on the area of injection.

Now about the differences between biorevitalization and contour plastic surgery. There are three types of biorevitalization procedure:

Injection.
Laser.
OXY therapy.

The advantage of biorevitalization is the possibility of restoring the skin without injections, i.e. it can be performed using a non-injection method, which is carried out on the face, hands and décolleté.

If the specialist is unqualified and violates the technique of performing the procedure, as well as if the patient violates the doctor’s instructions, the biological process of skin aging may not slow down, but accelerate.

When do you need calcium hydroxyapatite paste?

As mentioned above, the drug is used in dentistry. Calcium hydroxyapatite is the main component of dentin and enamel tissues. Therefore, it is widely used for dental restoration and the manufacture of dentures. The substance is used by dentists for a variety of purposes, but can be found in common home remedies.

Throughout life, teeth are exposed to many external factors that can weaken them. They experience processes of de- and remineralization. Saliva has a special influence on the condition of teeth, since it contains the components necessary for the synthesis of Hydroxylapatite. This is how remineralization occurs. Ingested food, especially with sugar, disrupts the acid-base balance. This is how the demineralization process begins, calcium and phosphorus are washed out.

There are several ways to restore tooth enamel and strengthen them. Firstly, all the necessary substances must come with food. Therefore, the diet should include foods containing calcium and phosphorus. But external protection of teeth with the help of special compounds and pastes will not be superfluous.

There are a considerable number of products that are aimed at restoring enamel, cracks, gullies, and fighting bacteria and plaque. They are divided into two main groups:

containing any calcium compound: glycerophosphate, lactate, citrate, pathotenate, hydroxyapatite. But it is important that the composition does not contain fluoride.
containing fluorine compounds: aminofluoride and sodium fluoride.

Enamel is the hardest tissue in the human body. They have a translucent color. But as a result of external factors, it becomes covered with plaque, spots appear on it, it loses its shine, and the balance between remineralization and demineralization is disrupted.

A paste containing calcium or fluorine compounds will help solve all these problems. Regular use of remineralizing products can postpone a trip to the dentist and keep tooth enamel strong and healthy.

But you shouldn’t assume that a filling from a doctor can replace it. Calcium hydroxyapatite paste helps improve the appearance of teeth, strengthen them and prevent problems.

We recommend reading about the best fillers under the eyes. From the article you will learn about how fillers work, the pros and cons of the procedure, the best fillers under the eyes for wrinkles, bruises and bags. And here is more about the features of the rejuvenation technique with Radiesse.

Calcium hydroxyapatite helps restore youth and beauty. It restores firmness and elasticity to the skin and makes the oval of the face clearer. But in the hands of an inept cosmetologist, it can cause serious harm, which is difficult to get rid of.

There are restrictions for specific drugs

They use either ready-made drugs or hyaluronic acid, which needs to be diluted.

Popular drugs:

"Aquashine";
Teosyal meso;
Jalupro;
IAL-System;
Juviderm Hydrate;
Meso-Wharton;
Yvoire Hydro;
Restylane Vital;
Filorga M-HA 18.

The preparations moisturize the epidermis at the cellular level, smooth out relief and wrinkles, improve complexion, and make it radiant. After applying the composition, the tightening effect is noticeable, the tone and elasticity of the skin returns.

The huge number of demands from clients of beauty salons has provoked the emergence of an equally large list of drugs, each of which is aimed at a strictly defined problem. The difference in requirements is the reason for the diversity in the composition of the substances introduced, and this, in turn, determines that each of them has its own limitations for use.

Aquashine

Aquashine is considered one of the most effective means for biorevitalization. The action of the composition is aimed at eliminating such manifestations of skin aging as:

dryness,
pore expansion,
excessive or insufficient sebum production,
the appearance of wrinkles.

Unlike basic preparations, Aquashine contains not only hyaluronic acid, but also 2 dozen amino acids, minerals, vitamins and peptides, which is why the following are prohibited from performing this procedure:

intolerance to any component,
pregnancy,
exacerbation of chronic diseases,
oncological diseases,
diabetes.

Revy Diamond

Biorevitalization Revy Brilliant can really stop the aging process.

A one and a half percent concentration of hyaluronic acid thickens the gel introduced into the skin, and the remaining components of the composition are capable of:

strengthen local immunity,
neutralize free radicals,
relieve swelling and remove excess fluid.

Revy Diamond is the name of a line of products that includes 3 drugs intended for different ages:

Revy Silver, used for clients from 30 to 45 years old;
Revy Gold, which helps restore the epidermis at the age of 45-55 years;
Revy Platinum, prescribed after 55 years, has the most “strong” and effective effect.

Expert opinion

Alexandra Mityaeva

Cosmetology expert

Carrying out a procedure using these substances is prohibited for those who are carrying a child or breastfeeding him or who have cancer.

Teosial Meso

The drug Teosial Meso is a development of scientists from Switzerland, made relatively recently, but has already won many positive reviews.

The drug performs the following functions:

smoothes even deep wrinkles;
reduces the number of pigmented areas;
tightens pores;
increases the volume of some parts of the face and outlines its oval.

Its use has no restrictions on the age at which it can be used for biorevitalization, and it is prescribed only after assessing the general condition of the dermis, but it is contraindicated for:

epilepsy,
skin diseases of various natures,
pregnancy,
oncology.

Ivor/Ivoire

Biorevitalization Ivor is indicated for:

dryness and sagging skin;
the presence of small wrinkles;
injuries due to the use of chemical peels.

Useful video

Watch this video about the procedure for introducing a filler containing calcium hydroxyapatite:

Answers on questions

Is it safe to use calcium hydroxyapatite?

Many years of experience have not revealed any negative consequences of using the medicine. Permission for use has been obtained in the countries of the European Union and in Russia.

Is it possible to combine the administration of the drug with other types of fillers?

Do not use with fillers containing hyaluronic acid. It is necessary to postpone administration until the expiration date of previously administered drugs.

Is it possible to use the drug calcium hydroxyapatite for the problem area located under the eyes?

The manufacturer does not recommend it, since the skin in the eye area is characterized as thin and sensitive. To treat this area, it is necessary to use more liquid formulations.

To what depth are injections made to administer calcium hydroxyapatite?

According to the technology, injections are made to the maximum depth until the needle stops in the bone. This method ensures better absorption of the product in the problem area.

Collagen based fillers –

Collagen is the main part of the dermal layer of the skin (dermis). The amount of collagen in the skin makes up 70% of its dry mass, and it is thanks to this protein that the skin has strength and elasticity. There are a total of 11 different types of collagen found in the skin, but the predominant types are collagen types I and III. Manufacturers use these same types of collagen to produce fillers, but their origin may be different. It can be bovine, porcine or bioengineered human collagen.

Collagen fillers have been used since 1981. The first fillers were made from bovine collagen (Zyderm 1, Zyderm 2 and Zyplast®). The production of modern collagen fillers uses the achievements of genetic engineering, or the innovative Israeli technology Glymatrix®, which allows you to start the process of formation of new collagen in tissues, and also extends the effect to 12 months. However, it should be noted that in Russia injections of collagen fillers are very rare (unlike Europe and the USA).

1) CosmoDerm® and CosmoPlast® fillers –

Fillers of this type include CosmoDerm 1, CosmoDerm 2 and CosmoPlast®. They are produced by the innovative American company Allergan Inc., which, by the way, is also the manufacturer of the drug Botox®. The production of these fillers uses bioengineered human collagen, which is obtained by culturing fibroblasts in vitro. Fibroblasts produce collagen, which is then used in the production of these fillers.

CosmoDerm 1 contains 35 mg/cm3 of bioengineered human collagen and a 0.3% lidocaine solution. This filler is most often used to treat superficial wrinkles and scars, such as wrinkles around the eyes or smoker's lines around the lips. In CosmoDerm 2, the amount of collagen will be 2 times greater, and this filler is more often used to eliminate post-acne scars. CosmoPlast also contains 35 mg/cm3 of collagen, but due to the use of glutaraldehyde, this drug undergoes slower breakdown than the first two.

Therefore, CosmoPlast is used to eliminate deeper wrinkles and atrophic scars, and very often often in combination with hyaluronic acid fillers. In this case, a voluminous tissue base is created using collagen filler, after which a more superficial injection of hyaluronic acid filler is performed into the same area. The advantages of CosmoDerm and CosmoPlast are that they do not require skin tests and produce less swelling and hemorrhage compared to hyaluronic acid injections. Disadvantages - high price, duration of action 3 and 4 months, respectively.

2) Evolence® fillers –

Evolence filler is the most innovative collagen-based filler that is just becoming widespread. Today it is used in Europe, Israel and the USA. , Israel. The drug contains porcine collagen types 1 and 3 in an amount of 35 mg/cm3. In the production of the drug, a number of cutting-edge technologies are used that make it possible to make pork collagen completely immunologically compatible with human collagen, but the most important thing is the Glymatrix® technology.

This technology makes it possible to bind collagen with the polysaccharide D-ribose, which gives collagen a certain three-dimensional structure, which is preserved even after the drug is introduced into the tissue. This three-dimensional framework is used by the patient's skin fibroblasts to produce their own collagen, triggering the processes of neocollagenogenesis and neovascularization. At the same time, the activity of fibroblasts in the skin, producing new collagen, increases noticeably.

There are 2 forms of release of this filler - Evolence® and Evolence® Breeze. The first is used to correct deep wrinkles and folds on the face, and can be applied to the middle and deep layers of the skin. The second has a less fibrous consistency and is used to eliminate fine wrinkles, to change the contour of the red border of the lips, as well as the shape of the body of the lips. Clinical studies conducted by Rzany, Monstrey and co-authors (involving a total of 740 people) showed that the effect after Evolence lasted at least 12 months, and in some patients lasted up to 18 months.

Evolence® filler injections –